The DNA helicase RECQL4 is known for its roles in DNA replication and repair.RECQL4 mutations cause Carafe several genetic disorders including Rothmund-Thomson syndrome (RTS), characterized by developmental defects and predisposition to osteosarcoma.Here we reprogrammed fibroblasts with a heterozygous RECQL4 mutation (c.1878 + 32_1878 + 55del24) to
Abstract Background Tetanus toxin blocks the release of the inhibitory neurotransmitters in the central nervous system and causes tetanus and its main form of prevention is through vaccination.The vaccine is produced by inactivation of tetanus toxin with formaldehyde, which may cause side effects.An alternative way is the use of ionizing radiation
Summary: The epidermal growth factor receptor (EGFR) plays a role in Glycine cell proliferation and differentiation during healthy development and tumor growth; however, its requirement for brain development remains unclear.Here we used a conditional mouse allele for Egfr to examine its contributions to perinatal forebrain development at the tissue
False rosemary is found on the backsides of foredunes, on all sides of backdunes, and inland in scrub communities.False rosemary is killed by fires but will reseed to an area in the absence of further disturbance.It is endemic to west Florida Corn Silk and Alabama, contributes to beach mouse habitat, and attracts many pollinators.https://edis.ifas.